Researchers at the University of Oxford have launched a trial that will deliberately expose people who have already had Covid to the coronavirus again to study the level of immune protection needed to prevent reinfection (assuming reinfection is possible). It is hoped that the study will aid the development of treatments and vaccines. The Guardian has the story.
The first human challenge trials for Covid began this year, with the study – a partnership led by researchers at Imperial College London among others – initially looking at the smallest amount of virus needed to cause infection among people who have not had Covid before.
Now researchers at the University of Oxford have announced that they have gained research ethics approval for a new human challenge trial involving people who have previously had coronavirus. Recruitment is expected to start in the next couple of weeks.
“The point of this study is to determine what kind of immune response prevents reinfection,” said Helen McShane, a Professor of Vaccinology at the University of Oxford, and Chief Investigator on the study.
McShane said the team would measure the levels of various components of participants’ immune response – including T-cells and antibodies – and then track whether participants became reinfected when exposed to the virus.
Participants must be healthy, at low risk from Covid, aged between 18 and 30, and must have been infected with the coronavirus at least three months before joining the trial. As well as having previously had a positive Covid PCR test, they must also have antibodies to Covid. Given the timing criteria, McShane said it was likely most participants would have previously been infected with the original strain of the virus.
The first phase of the trial will initially involve 24 participants split into dose groups of three to eight people who will receive, via the nose, the original strain of coronavirus. The idea is to start with a very low dose and, if necessary, increase the dose – up to a point – between groups…
The second phase of the study – expected to start in the summer – will involve a new group of participants and will study closely their immune response before and after exposure to the virus, as well as the level of virus and symptoms in those who become reinfected.
The vaccines which produce the required level of immunity – as determined by this study – could have their licensing fast-tracked without trials of thousands of people, according to Professor McShane.
If we can determine the level of immune response above which an individual cannot be infected, then that will help us determine whether new vaccines will be effective without necessarily having to test them in phase three efficacy trials.
Worth reading in full.
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More outrageous voodoo medelling.
Won’t it be a surprise when the vaccines are proven to work?
I don’t know how people like this McShane character sleep at night. All for forty pieces of silver.
Sooo …. ‘Covid’ is not the deadly disease that has been billed. Otherwise no-one would propose such an experiment. This puts it at the level of the common cold, I guess.
The contradictions that are beginning to emerge in a flood are legion.
But my bet is that the hypnotised will not be easily de-programmed.
Can you imagine: “We’re trying to test a new vaccine, so we decided to infect people with HIV to see how it works.”
I’ve noticed that many sceptics have started to caveat their statements with prefaces such as “I don’t deny the virus is severe but…”. Well, I don’t do that because I believe that the data is showing something perhaps as serious as a bad cold, but for which there was little existing immunity last spring, and was helped out by awful government policy and woeful NHS infection control.
I am afraid that this is, and will eventually be known as, a type of common cold, unless the “vaccines” enhance it.
Yes – that habit of making obeisance to the official narrative : ‘awful/deadly disease’ ‘virulent’ ‘unprecedented pandemic’ etc. etc. has constantly pissed me off, too!
double mutant variant
Was just going to post the same thing. You never see these sorts of experiments being done with Ebola do you? Almost as if they’re suggesting the risk to under 30s is so small as to be entirely insignificant. Still, let’s forcefully vaccinate them!
Add one more to the list.
A virus so deadly that:
This is getting ridiculous. Seriously, if by this point you haven’t figured this out yet, what is wrong with you?
Worth adding that:
This will show people getting infected with whatever it is that the PCR test finds. But the people will not be ill.
So it will be a rationale for perpetual panic.
I recommend the book Virus Mania or Dr Joanne Bailey on You Tube for a non orthodox perspective on what is going on.
By the way, I took the vaccine but am increasingly doubtful that this was smart.
Please explain why this is worth adding and what it is?
https://youtu.be/huEaH-boaoY
Depends how term what an isolate is.
There is a 1m dollar prize for someone who can prove they have achieved it for SARS-CoV-2.
Are you new here?
why this is worth adding?
Not sure if you are really unaware, but please watch Dr Sam Bailey, YouTube, virus isolation. That should explain it to you.
She does not say why it is worth adding. Do you think it is worth adding, and why?
So i see you haven’t watched the video two people so far have told you to watch. Do you think it’s worth asking the same question over and over without looking at the answers you are given?
Sure I saw someone reply to this guys response on another post as 77th Brigade nonsense. Had to go google what that was – but makes sense?
I need you to come round and speak to my husband
I am waiting for an offer to get infected in return for a 10 year guarantee of never being subjected to any test, muzzle and gene therapy.
And that’s somewhat negotiable too.
And what would their guarantee be worth?
More vaccines, more money. Kerrching!
I smell a rat. Didn’t they already announce a challenge trial?
It stinks is what is does. STINKS
Clearly a set up for the narrative that ‘oh, your immune system won’t fight it off for very long. You need this vaccine. It’s compulsory’
https://www.gov.uk/government/news/worlds-first-coronavirus-human-challenge-study-receives-ethics-approval-in-the-uk
If it’s the same trial, it’s been delayed for a month and has a third of the participants. What kind of freaky ethics committee opts green lights this kind of study? Are these the same ethics committees that won’t do a vaccinated versus unvaccinated study for children? Or that insist on the placebo being another vaccine to another disease rather than being saline? You know, I am coming to believe that the UK has become the Africa of Pharmaceutical testing in the West. We’re ground down, impoverished, over-medicated and unsuspecting. We have no Democracy to speak of, no constitution which enshrines our rights, and our best academic institutions and their occupants have been paid for by money from outside the country, funnelled through our own institutions, or indeed there in plain sight as “grants”. What are we doing? And if you believe that this was a gain of function experiment gone wrong in Wuhan, why are you replicating the methodology in the UK? Surely we have to stop experimenting on our own people and start focusing on old fashioned British wisdom, grit and decency. Feed a cold. Starve a fever. Good diet. Eat less carbs. Take up meaningful work. Supplementation… Read more »
BioEthics is a field that justifies the unethical.
I would really like to know where they get the virus from and how it will be presented.
This was also done in 1918. With US Navy prisoners who volunteered in return for reduction of sentences.
They were chosen because they had not had flu before. The studies allegedly failed to infect a single prisoner.
Reality is that we do not really understand transmission of this illness, nor what causes it.
Would this be the same year we got a pretend pandemic cover-up, the ramifications of which have been holding us prisoners for over a year. Complete with silly stories about people who had the temerity to celebrate the end of war, and a town that locked down, only to get infected when it eased that lockdown. And which gave us the book Pale Rider, do conveniently released in time for the pandemic?
With stories of nurses who succumbed to the disease their infected soldier patients were spreading. You really couldn’t make this tripe up. And yet you can. And someone did.
The first phase of the trial will initially involve 24 participants split into dose groups of three to eight people who will receive, via the nose, the original strain of coronavirus.
I’m confused. Does this mean they have stocks of isolated pure virus? I know there is still a reward for anyone who can prove this.
https://www.samueleckert.net/isolat-truth-fund/
I would really like to read the papers on this research on how, where and when. I look forward to their publication.
I want to see the deliberations of the ethics committee.
“…will receive via the nose” … as when they thrust those lanky Qtips up your nostrils to swab a sample?
“Professor of Vaccinology “
So by putting a vaccine-monger in charge, what answer are they likely to get? If you have a hammer, everything looks like a nail. A bit like putting blind faith in modellers when making policy decisions.
Well I suppose they can’t launch a trial of the vaccine where they deliberately infect vaccinees because we already have one, in which over half the population have participated, with a mere 830+ deaths…
… so far!
And what became of this trial?
https://www.theguardian.com/science/2020/jul/16/coronavirus-vaccine-oxford-team-volunteers-lab-controlled-human-challenge-trial
When are they due to start the human challenge trials for flu?
The only UK trial I wish to read about is that of Bozo, Witless, Hancock et al – and I hope the judge will be wearing a black hat!
We can but dream! I’m afraid you are more likely to see a pig flying past your window than that happening.
I smell a rat!
“Ever get the feeling you’ve been cheated?” – John Lydon 1978
immunity does NOT prevent infection … it prevents sickness … with a 40 cycle PCR I would expect everyone to get “reinfected” …
But these young people are not the people who can benefit from a vaccine. They mostly don’t get serious complications from infections so how can a vaccine based on their age group help older people?