Research on mice has found that exposure to the SARS-CoV-2 spike protein by itself, without the rest of the virus or any viral replication, is enough to cause COVID-19-like symptoms, including severe inflammation of the lungs. Dr Pavel Solopov, Research Assistant Professor at Old Dominion University in America, who led the research, told the Medical Xpress:
Our findings show that the SARS-CoV-2 spike protein causes lung injury even without the presence of intact virus. This previously unknown mechanism could cause symptoms before substantial viral replication occurs.
The researchers injected genetically modified mice with a segment of the spike protein and compared them after 72 hours with a control group injected with saline. The outcome was unmistakable, according to the Medical Xpress.
The researchers found that the genetically modified mice injected with the spike protein exhibited COVID-19-like symptoms that included severe inflammation, an influx of white blood cells into their lungs and evidence of a cytokine storm – an immune response in which the body starts to attack its own cells and tissues rather than just fighting off the virus. The mice that only received saline remained normal.
The researchers did not, according to this report, indicate whether the finding has any significance for the vaccines and their side effects. The Pfizer, Moderna, AstraZeneca and Johnson & Johnson vaccines all work by delivering genetic material that induces cells around the body to produce the spike protein, which the immune system then becomes primed to recognise. A question arising from this research is whether, if the spike protein is pathogenic in its own right and not just a means of gaining entry to cells, this explains any of the Covid-like side-effects of the vaccines, including some of the rare serious ones.
Other research has suggested that “the SARS-CoV-2 spike protein (without the rest of the viral components) triggers cell signalling events that may promote pulmonary vascular remodelling and pulmonary arterial hypertension as well as possibly other cardiovascular complications”. These matters should continue to be investigated.
Worth reading the Medical Xpress report in full.
(Image: Using a newly developed mouse model, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation in the lungs. The left images show healthy mouse lung tissue while the right images show tissue from mouse lungs exposed to the spike protein. Credit: Pavel Solopov, Old Dominion University.)
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re:The researchers did not, according to this report, indicate whether the finding has any significance for the vaccines and their side effects.
translation THERE IS NO REASON TO THINK or even suggest the finding has any significance for the vaccines and their side effects.Hence it’s a hogwash anti-vaxx story.
1) Spike protein alone causes covid-19-type lung damage
2) covid-19 vaccines involve creation of covid-19 spike protein in human body.
By inference we would normally form a scientific hypothesis – eminently worthy of investigation – that the vaccines may cause lunge damage on the basis that they create a spike protein implicated in lung damage. However, by invoking Fon’s Theorem (that one suspend all cognitive function in cases in which inference or deduction may legitimately be performed) we can see that any such hypothesis is patently reduced to absurdity.
So how is this spike protein expressed primarily in cells around the muscle area going to get to the exterior of the lungs in any useful number?
Especially when applied as a low dose and/or in a non-replicating vector?
Is it going to grow little legs and start walking?
If the jab is injected into the bloodstream, what makes you think it doesn’t spread around the body?
All of the shots are designed to deliver instructions to cells all around the body to create this spike protein and ‘anti-body’ for it; there’s no reason to think that this can’t happen in lung tissue just because you got the jab in your arm.
All that said… they are developing a nasal spray version of this “vaccine”, so even using your (lack of) logic this all is still quite relevant.
Non replicating vector? Perhaps in ape adenovirus in Astra but in the Russian sputnik vaccine the human adenovirus used seems not to have been killed in practice vaccinating against two viruses instead of one.
https://twitter.com/angie_rasmussen/status/1387397186372005893
I would not bet that not a single spike protein escape the intramuscular site and enters the circulation.Whether it is in a minute amount and a non issue is possible but that this deserves a serious investigation is self evident.
It’s not that it wasn’t killed. But the story is quite interesting. In order to replicate an adenovirus needs its E1 gene. You make the vaccine by replacing E1 with the antigen (in this case the spike). This means it can make spikes, but not copies of itself. But then how do you actually produce the vaccine? You culture it in cells which themselves make E1 from their own genome. So E1 is around and the vaccine can therefore replicate inside those cells. The cells they culture them in are HEK-293. These are human embryonic kidney cells all cloned from some aborted foetus long ago. So how come they express adenovirus E1 when they’re human kidney cells? Well they aren’t regular human kidney cells. They were actually hybridized with– you guessed it– human adenovirus 5 back in the 1970s. So the Sputnik vaccine (which is based on Ad5) is cultivated in cells which are hybrids of Ad5. This unfortunately means that every now and then the E1 gene from those kidney cells swaps back into the vaccine, and you end up with a fully functioning adenovirus. Fortunately Ad5 is endemic anyway. If AZ pulls this stunt (which it might– it’s… Read more »
I thought the whole point of the MRNA vaxxes was to create covid spike protein “factories” in the body.
It wouldn’t be much use if it sat and sulked in your arm, would it?
Wouldn’t be mostly ‘armless. I’ll get my coat…
“non-replicating vector” uhuh. You might as well ask how CJD prions turn up in the CNS? But they do.
That’s the kind of question which should be addressed in trials of all new vaccines …. to rule out … oh wait.
Read the attached, educate yourself, then apologise for posting rubbish.
https://www.wodarg.com/english/
It’s called the circulatory system.
ACE2 is present in many cell types and tissues including the lungs, heart, blood vessels, kidneys, liver and gastrointestinal tract. It is present in epithelial cells, which line certain tissues and create protective barriers.
You really don’t have the foggiest idea about trialing medicines, and why using any after this sort of period is beyond stupid, do you?
You really are into religion rather than science.
Sorry, your advocacy for untested genetic engineering of the healthy human population is just sick and deranged at this point. You should at least be calling for the vaccine rollout to be paused while this is investigated. To colour anyone with concerns about such medicines as anti-vaxx just shows how low you can go. Healthy people are dying horrible deaths because of your sick agenda. Imagine if it were someone you cared about.
The provocateur cares little about anyone.
You had both your jabs then, fon?
Don’t you know anyone yet who’s had a bad reaction to a so called covid vaccine? You must be in a minority. We don’t need research studies to tell us that people are having a bad time with these injections.
Not a very sophisticated response even for a pro vaccine person.The latest concern raised is that the antibodies developed in VITT cases might occur in a low level for ordinary vaccinated persons and might increase with time in line with an autoimmune response.Astra need to do studies urgently to exclude this especially for those 1-10 % which have a slight temporary thrombocytopenia with the vaccine.
Might not agree with everything in this new German article especially the very pessimistic view what could happen but this need urgent investigation.
https://1bis19.de/wissenschaft/toedliche-autoimmunerkrankung-bei-ca-10-der-mit-astrazeneca-geimpften/
If translation needed there will always be someone to do it at the 77th Brigade which seems well funded
VITT, that’s the blood clotting/low platelet cases associated (in a very small way so far, but then the vaccines have mainly been focused on the elderly) with all the vaccines.
“The researchers did not, according to this report, indicate whether the finding has any significance for the vaccines and their side effects.”
They also didnt deny that it has significance. Therefore your interpretation of the statement is wrong. They might not have said anything but the evidence of the science looks pretty clear. The spike protein can cause Covid on its own at least in mice.
Now it might not cause Covid in humans, but there is enough here to call a halt to the vaccinations.
And poor Fon accused RealArthurDent of being dim!
So the NHS has been doling out “long covid”?
It is striking that many of those with bad reactions to the jab have symptoms which could be Covid itself, and if they are on Spector’s app are advised to get tests. Of course some of those are typical immune reactions, but some not.
Well done Will, thanks for covering this. Whether or not it has implications for the vaccines, it’s a very important study.
One which should have been done BEFORE they were invented
Best not to snort the vaccine then.
Good luck finding a mechanism where a non-replicating virus is going to somehow migrate to the lungs, bypassing all the other similar receptors en route.
Seem like the kind of thing that would be picked up in essential clinical trials that all medicines need to go through before being offered to the public.
Quod erat …
You have to have a stonking good reason to rush to encourage the use of an unapproved medicine.
There is no such reason embodied in SARS-CoV-2.
That’s why long term trials are long term. Time’s arrow matters.
An acquaintance of mine (female, 40s, family jabbed early because of a clinically vulnerable child) was advised to attend hospital this week with suspected clot in the lung.
Nah – nothing to see here…..
“The researchers did not, according to this report, indicate whether the finding has any significance for the vaccines and their side effects”
Yes, they wanted to get published.
Mike Yeadon makes the point that while these mRNA treatments cause the body to create the Covid spiked protein, there is seemingly no way to control how much of it is generated within the body (or even in which cells they are generated), unlike in a normal vaccination which delivers a precise amount, tailored to the patient.
100% There’s no “OFF” switch.
Cells will just keep creating this spike protein. Another name for the type of cell that continuously creates and spews out proteins to no end is a CANCER CELL.
There is also now (anecdotal) evidence that those who have gotten this EXPERIMENTAL jab are actually transmitting these spike proteins to those around them. There are reports where children who did not get the shot but who live with a parent that did are getting nose bleeds, and there appears to be blood clotting issues with un-“vaccinated” adults who are around people that have gotten the jab.
I don’t want to seem like an ally of Fon, but by what possible mechanism could that happen? Do these unfortunate children also test positive? You’re implying that the vaccinated develop a truncated form of spike created virus and breathe out plumes? There’s a lot of obvious, grounded worries without going into this territory.
I read the same thing elsewhere – non-vaccinated women becoming infected by vaccinated people and having miscarriages. Perhaps we need to be protected from those who’ve been vaccinated?
Asking for a mechanism? Please, that would be scientific.
Yes and what happens if these cells are created in the vital organs such as the liver & kidneys as they try to excrete it? What happens when genetically modified human waste enters the wider environment? Has it been tested or risk assessed? Nobody can answer these questions. It is all so very short sighted.
This may or may not be an important paper and the vaccines may be a modern marvel or may have long term hidden dangers.
What we really need is an open and honest atmosphere where scientists do their work in the traditional sense. No de-platforming scientists or not publishing work that doesn’t ‘fit the narrative’
And there’s your post-vaccination spike in deaths. fab.
https://www.achgut.com/artikel/warum_sind_die_covid_impfstoffe_so_toxisch
More on the toxic spike proteins.
Bhakdi’s new hypothesis explained.
And: the gene therapies are basically just placebos with unknown dangerous side effects: you basically just take them to feel better/less discriminated against.
Erm, experienced virologist etc have been pointing this out for over 12 months, why do these people keep needing to reinvent the wheel?
Of course its the bloody spike, which is why the various vaxx have tried to replicate it, with anyone with half a brain saying you can’t pump that into humans until we know exactly where those spikes are going, like the brain?
Give me strength!
The control was saline, but they did not try a (presumably denatured) protein of similar size but different composition. Seems a bit lazy not to got that bit further, but at least some mice were spared some pain (for a while).
What we need to see here is how much of the stuff they injected into the mice. Most studies of this kind involve injecting the poor bastards with doses thousands or 10s of thousands higher than what people are being exposed to. If you do that it’s not surprising that bad things happen.
However it is known that spike can cause problems just on its own. Some people think this might be behind the clotting problems (although I don’t think so, I think that’s something different).